+123 456 7890 1600 Amphitheatre Parkway Mountain View, CA 94043

The Design Packed Into a Fruit Fly

first_img(Visited 437 times, 1 visits today)FacebookTwitterPinterestSave分享0 How Fruit Flies Navigate for Miles Over the DesertIt’s been awhile since we heard about the latest research in the Dickinson Lab at Caltech. In 2003, Michael Dickinson dazzled us with descriptions of the navigation abilities of the tiny fruit fly, Drosophila (8 Dec 2003). The lab is still in operation, ready to dazzle us with another feat of the minuscule flyers: celestial navigation. A press release from Caltech says,What do ancient seafaring explorers and fruit flies have in common? Caltech researchers have discovered that, similar to nautical navigators of old, fruit flies use celestial cues like the sun to navigate in straight lines.The research is described in a paper appearing online on August 30 in the journal Current Biology. The work was done in the laboratory of Michael Dickinson, Esther M. and Abe M. Zarem Professor of Bioengineering and Aeronautics.The article asks us to ponder the challenge of walking in a trackless desert, with no landmarks, yet needing to keep in a straight line.This is the conundrum of Drosophila, the common fruit fly, in the desert. Almost 40 years ago, a study found that fruit flies can fly up to nine miles in one night in search of food and water. How are these tiny insects able to navigate such long distances?“For flies crossing inhospitable territory, flying around in circles would be really dangerous—they’re less likely to find any food or water,” says postdoctoral scholar Ysabel Giraldo, the study’s first author. “Surprisingly, fruit flies are seasonally found in environments like the Mojave Desert. They must get there from somewhere, and once there, they must figure out how to get around.“Using Dickinson’s ingenious flight simulator, researchers found, to their astonishment, that the little flies can use the sun as a marker. They will fix a bright spot in one position in their visual field and stick with it for long distances. “It was a bit surprising to find that the same pesky little flies that flit around fruit bowls and wine glasses have the capacity to navigate for many miles using the sun,” Dickinson said. The flies come equipped with “compass neurons” to do this. Researchers used genetically modified neurons to watch active neurons light up, using a powerful microscope to peer through tiny holes in the fly’s head while it was on the flight simulator. To work, the compass neurons must be able to integrate their information and then signal the muscles of the wings to stay on course.Most likely, well-known migrating insects like Monarch butterflies also come equipped with specialized neurons for their multi-thousand-mile migrations. Fruit flies, however, are much smaller, so their equipment represents micro-miniaturization of the bio-technology. Information on the Dickinson paper can be found at Caltech Coda.Evolutionists believe that fruit flies have been navigating like this for many millions of years, but they didn’t say how the ability emerged by chance mutations and natural selection.How Sustained Flight Is MediatedThey have fruit flies in India, too, and researchers there found one component of a system that allows for sustained flight. So what’s all the excitement about flight? A press release from the National Centre for Biological Sciences (NCBS) at the Tata Institute of Fundamental Research (TIFR) asks that question, and describes what they found.Have you ever wondered how tirelessly the tiny fruit fly buzzes around your fruit bowl? This behavior not only demands tremendous energy but also requires highly coordinated neuronal signaling that enables continuous flight. A recent study from Prof. Gaiti Hasan’s lab has uncovered molecules required in the fruit flies brain that enables flight for long periods of time and helps them locate the fruit bowl in your pantry. One of the key proteins identified in this study is the FMRFa receptor (FMRFaR). The authors describe a role for this receptor in a specific class of neurons in the adult fly brain which helps the fly sustain flight for long periods of time.This receptor is a member of the family of G-protein coupled receptors (GPCRs), known to convert hormonal signals into actions. The team found that mutant flies without FMRFaR could only fly about half the time.A fruit fly body is only a few millimeters in length.“One would expect that flying for several minutes at a stretch would require a continuous stream of sensory information for the fly to reach its destination. Here, we believe that the FMRFaR on dopaminergic neurons helps in processing such sensory information and thus enables sustained flight in the right direction”, says corresponding author, Prof. Hasan.Many questions remain, however, such as the source of the information that triggers the protein. The FMRFaR protein has a length of 549 amino acids, according to the UniProt database. The Illustra Media film Origin showed that the probability of getting a protein less than a third that size (150 aa) would never happen by chance in the history of multiple universes.How much design do you need to see before you give up on Darwinism absolutely and forever? The most amazing animals of all may be the tiniest. Consider how much bio-technology has to fit into the head of a fruit fly.last_img read more

Read More »

How Big Brands – With Help From Google & Yahoo – Finance Online Piracy

first_imgA Web Developer’s New Best Friend is the AI Wai… Are major brands funding online piracy? The answer is yes, even if they’re not fully aware of what they’re doing.That’s the clear conclusion of a recent report out of USC’s Annenberg Innovation Lab, which says the top ad networks finance 86% of sites that feature illegally distributed content. The results, which named Google and Yahoo among the top offenders, used Google’s own Transparency Report to name the 10 ad networks with most takedown requests under the Digital Millennium Copyright Act (DMCA) for copyright infringement on pirated sites. This dirty secret is hardly unknown within the industry: Most advertisers, big and small, engage in it. But the general public has been relatively in the dark. The USC report is intended to let the public know what’s really going on, on a planned monthly publishing basis.“A lot of major brands are advertising on these pirate sites,” says Jonathan Taplin, the director of the USC Annenberg Innovation Lab, and the man behind the project. The irony is most aren’t even aware of it, he says. Still, he thinks this trend can be changed.Taplin says that when he notified Levi’s, a partner of the Innovation Lab, the jeans giant “called their [ad] agency and said: ‘Take our stuff off these pirate sites.’ And within two weeks, we could see a change completely. So I know it’s possible.”Fighting Piracy Taplin, who previously spent time as a film producer and music manager, was drawn to this research after watching the late Levon Helm, a close friend and drummer for The Band, lose much-needed royalty income due to peer-to-peer sharing sites like LimeWire. Saddled with heavy medical bills and a mortgage, Helm “had to go back on the road with Stage Three throat cancer,” Taplin remembers somberly. “Some nights he could maybe sing one song… When he died last year, a bunch of musicians got together, threw a benefit for him at Madison Square Garden in order to pay off the mortgage on his house so his wife wouldn’t get thrown out on the street.”  Taplin didn’t believe legislation like SOPA and PIPA would solve these copyright problems, and decided to investigate the online ad world. He found a fragmented, poorly understood business full of middle men and companies in the dark about where their ads were actually being placed, and what he considers parasites on the creative community raking in the loot.“The ad networks are a pretty Wild West kind of world,” he says. “I don’t think that the brands know where their ads are going. There’s no real accounting or auditing how this works.”The main problem is that most brands pay third-party ad networks to make ad buys and get them eyeballs. Most aren’t aware where those viewers come from. As long as the targeted number is hit, that seems to be all that matters.  “What happens is a brand comes to an ad agency and says we want 5 million impressions on the Internet with a demographic profile of males 18-26, because we’re selling auto insurance,” Taplin says. “So the agency then farms it out to an ad network. The ad network goes out and gets those impressions, but it could be that the easy way is to get a lot of impressions on the cheap inventory on pirate sites, where, needless to say, there are probably a lot of males 18-26 hanging out.”Taplin characterizes the industry as see-no-evil, hear-no-evil. “In some ways it may be that the brands or the agencies don’t really want to know where this stuff is ending up,” he says. “Google can assure someone that your ad is not going to end up on a porn site, so there’s probably no reason it couldn’t assure you that your ad is not going to end up on one of the top 800 sites that are on the Google Transparency Report.”See No EvilCameron Yuill, the founder & chief executive of AdGent Digital, says there are two very different kinds of advertising: branded content, and direct response, and he blames the direct response advertisers. “A lot of the direct response guys don’t care where their ad appears… they just want to get a response.”Is that an ethics problem? “I would say absolutely,” Yuill says. “It’s been part of the industry since day one, right? Trying to get people to click on an ad.” The online ecosystem’s easy self-service culture has resulted in many companies not knowing who they’re doing business with, says Jules Polonetsky, director and co-chair of the Future of Privacy Forum, and the former chief privacy officer and special counsel at DoubleClick (before it was acquired by Google).“The next thing you know a Fortune 500 advertiser is in business with some unknown blogger or some pirate site,” Polonetsky explains. “Clearly there are steps that companies can take in an automated way, but it’s a challenge. Most certainly have policies against it, the question is how good can your automated systems be to prevent it, or are you intentionally casting a blind eye?”Going ForwardTaplin’s goal is to publish these reports monthly to raise awareness in the industry.Right now his report details the top 10 ad networks with the most DMCA takedown requests. “Eventually we’ll have the top 20 ad networks, and maybe the top 10 of brands on these sites,” he says. “My hope is that it would begin to lead the industry to a code of best practices so they’re not going to do this anymore. I think the brands that want to be associated with music and film understand that they can’t on one hand sponsor a tour for rock and roll band, and the other hand be putting a lot of money into pirate sites…or a torrent site that has all of those movies for free.”Photo courtesy if Shutterstock. adam popescu Related Posts 8 Best WordPress Hosting Solutions on the Marketcenter_img Why Tech Companies Need Simpler Terms of Servic… Tags:#advertising#e-commerce#Google#piracy#privacy#security#Yahoo Top Reasons to Go With Managed WordPress Hostinglast_img read more

Read More »

Bihar alliance meant to protect the corrupt: Ravi Shankar Prasad

first_imgUnion Law Minister Ravi Shankar Prasad on Friday termed the ruling coalition in Bihar — made up of the Janata Dal (U), the Rashtriya Janata Dal (RJD) and the Congress — as a coalition “designed to protect the corrupt” after a court refused to stay an Income Tax probe in the National Herald case and a controversial land deal allegedly involving RJD chief Lalu Prasad and his family members. Mr. Prasad said the BJP would like the Central government to probe a tainted land deal allegedly involving Mr. Lalu Prasad and his daughter and Rajya Sabha MP Misa Bharti, and sought action against Ms. Bharti for reportedly not disclosing her property details in her election affidavit. Mr. Prasad’s allegations against both Mr. Lalu Prasad and the Gandhis were also aimed at questioning the efforts at oppositional unity around a common presidential candidate for the polls slated in July this year. He demanded that Janata Dal (U) leader Sharad Yadav and CPI(M) general secretary Sitaram Yechury, explain whether the alliance was meant to serve the people or individuals involved in corruption cases.last_img read more

Read More »

Manchester City Lose Appeal to CAS over Financial Fair-Play Investigation

first_img appealCASCourt of Arbitration for SportFinancial fair play First Published: November 15, 2019, 6:26 PM IST Get the best of News18 delivered to your inbox – subscribe to News18 Daybreak. Follow News18.com on Twitter, Instagram, Facebook, Telegram, TikTok and on YouTube, and stay in the know with what’s happening in the world around you – in real time. Manchester City have lost their appeal against the decision of UEFA to refer the English champions to its adjudicatory chamber over alleged Financial Fair Play violations, the Court of Arbitration for Sport (CAS) said on Friday.City reacted angrily when they were referred to the adjudicatory chamber of UEFA’s club financial control body by its investigatory chamber in May. The club said it would appeal to CAS, but the sports court dismissed their initial appeal, saying on Friday that City had not “exhausted the legal remedies available to it prior to the appeal”.It means City have failed in their attempt to stop UEFA from investigating the allegations they supplied false financial information, with CAS saying their appeal was “inadmissable”.The investigatory chamber had also recommended that City be sanctioned by UEFA.The investigation into City is based on leaked emails published last year by German magazine Der Spiegel as part of “Football Leaks”.Possible punishments include a suspension from the Champions League, a transfer ban or a fine. last_img read more

Read More »

VFI President terminated in EGM

first_imgChennai, Mar 3 (PTI) The Emergent General Body meeting and the Executive committee meeting convened by Volleyball Federation of India Secretary General Ramavatar Singh Jakhar today decided to terminate Chaudhary Avdhesh Kumar as VFI President. Jakhar alleged that Kumar had displayed “arrogant behaviour” in suspending 10 members and senior officer bearers” of VFI. “Today we had a crucial meeting and the entire house attended by 22 of the 29 affiliated Units of the VFI unanimously decided to terminate the President as he is acting arrogantly and he is not a normal man but behaving like a Hitler,” he said. Jakhar said, “Members considered his actions as unilateral, uncalled for and illegal in suspending the Core Committee appointed by the EC and freezing of VFI bank account in Chennai. His actions have proved that he is bigger than the VFI and the General body. The meeting condemned his actions in one voice.” Jakhar said the meeting passed a unanimous resolution to terminate Avadhesh Kumar as President of the VFI and this decision will be firmed up at the Special General Body and extraordinary meeting already convened to be held at Chennai on March 11. The internal war between the two factions of the Federation over the proposed Indian Volleyball League (IVL) resulted in Avdhesh Kumar suspending 10 members of the VFI for attending an “invalid” core committee meeting on February 22 in New Delhi. Kumar had suspended VFI CEO K Murugan, executive vice- president Raj Kumar and treasurer Ranjit Roy Chaudhary, along with seven other state unit affiliate members who attended the meeting called by executive vice-president Raj Kumar. He had also declared all decisions taken on Feb 22 meeting as null and void. Meanwhile, Jakhar, who had termed the suspension by the President as “illegal and unethical” had then said he would get those decisions overturned at todays meeting. The Secretary also announced that the “IVL will be held definitely in November and December this year jointly by the Core committee of the VFI and the Company”. “Todays meeting also cancelled the authorisation extended by Kumar to another Company to sponsor IVL without ECs decision. Instead, the EC today perused the four offers received from different sponsors and decided to extend the sponsorship rights to a Delhi-based sports marketing company Baseline.” PTI RE PM PMadvertisementlast_img read more

Read More »

Hyundai recalls 7,657 units of small car Eon in India

first_imgNew Delhi, Oct 4 (PTI) Hyundai Motor India is recalling 7,657 units of its entry level small car Eon to fix faulty clutch and battery cables. The recall will cover Eon units produced in the month of January 2015. The company has initiated a service campaign to recall and inspect the clutch cable fouling with battery cable of Eon cars produced in the month of January 2015, at no cost to customer, Hyundai Motor India said in a statement. “The company will voluntarily recall 7,657 number of Eon cars in India manufactured between January 1 2015 ? January 31 2015,” it added. Eon customers of respective period will be notified in a phased manner for inspection of the clutch cable fouling with battery cable and replace the battery cable if found damaged. The company asked owners of all affected Eon cars to take them to authorised Hyundai dealers. In 2014, the company had recalled 2,437 units of its sports utility vehicle Santa Fe to replace a faulty stop lamp switch. Over two million vehicles have been recalled by various automakers in India ever since the auto industry body SIAM started voluntary vehicle recalls for safety related issues in July 2012. PTI MSS RKL MRlast_img read more

Read More »

Tanaka Awesome, Yanks Take Twins

first_imgNEW YORK — Masahiro Tanaka shut down Joe Mauer and the other Minnesota hitters while lowering his American League-leading ERA to 2.06 as the New York Yankees downed the Twins 3-1 on May 31.Tanaka (8-1) permitted only one unearned run in eight innings. The heralded rookie from Japan gave up four singles, just two leaving the infield.Tanaka throws a splitter that drops out of sight, ranks among the major league leaders in many prized pitching categories and appears, so far, to be worth every penny the New York Yankees paid to sign him.He seems to have a different take than most everyone else. “No, I don’t feel that I’m the ace,” he said Saturday through a translator.Tanaka struck out nine batters, giving him 88 in 78 2-3 innings. The 25-year-old righty is removing more batters in the big leagues than he did back home before getting a $155 million, seven-year contract from the Yankees.“It’s probably the guys here haven’t seen me,” he said.Tanaka walked two and bounced two wild pitches. But he was especially sharp against Mauer, the three-time AL batting champion.Mauer, who faced Tanaka in spring training, struck out on three pitches in the first inning with a runner on third. Mauer fanned on four pitches with runners on second and third in the third, then tapped into a double play and later grounded out.“Guys said the ball was just disappearing,” Twins Manager Ron Gardenhire said. “His splitter is unbelievable, he’s got all the pitches.”Yankees first baseman Mark Teixeira left in the sixth because of soreness in his surgically repaired right wrist, the same problem that forced him to miss three games this week.It was 1-1 when Jacoby Ellsbury singled with one out in the Yankees eighth off Brian Duensing (1-2). Ellsbury stole second, and continued to third when catcher Josmil Pinto’s throw from his knees went into center field for an error.In light showers, Brian Roberts walked and Brian McCann hit an RBI double over leaping first baseman Chris Parmelee into the right-field corner. Following a 34-minute rain delay, Kelly Johnson drove in a run with an infield single.Tanaka and Twins starter Kevin Correia both escaped early trouble, and nobody pitched a perfect 1-2-3 inning until the seventh.David Robertson pitched the ninth for his 12th save. Yangervis Solarte homered for the Yankees’ first run.(BEN WALKER, AP Baseball Writer)TweetPinShare0 Shareslast_img read more

Read More »

Five Things We Learned From the Oklahoma State-Baylor Game

first_imgBaylor whipped Oklahoma State on Saturday night for the Cowboys’ first loss in 12 months. Here are a few things we learned from the 10-point thumping at the hands of two backup QBs.1. Baylor’s talent is much better than OSU’s (KP)I think most of us would have said Baylor had more talent coming into the game, but I can’t remember an outing during the good years of the Mike Gundy era (2008 and on) in which this was more apparent. It was stunning. OSU just got whipped over and over again on both sides of the ball and outraced in the secondary. Kyle, you and I could have tossed a few TDs on Saturday night with the horses Baylor rolled out there. That’s a scary thought for the future considering Art Briles isn’t going anywhere.Gundy: “I knew Baylor was a good team, but they’re fast, they’re faster than I saw on tape.” #OKstate— Andrew Carter (@Andrew__Carter) November 23, 20152. Running isn’t paramount, but it helps a lot (KP)Baylor just loaded up and ran it down OSU’s throat all night. It reminded me of what Gundy and Co. would do with leads during the Weeden years and Joe Randle would go for eight a carry almost every time (or that’s what it felt like — both with Randle and Baylor on Saturday). OSU proved that it doesn’t have to have a running game to win 10 times in a season. Baylor proved it makes it a lot easier to do so.3. This team is still young (KB)In a game where the Cowboys simply could not get anything going on the ground, Baylor’s veteran presence on the offensive line showed just how valuable a veteran presence can be. The Pokes are still very young on the offensive line with a lot of room to grow, but even key skill players are still relatively young. Guys like James Washington, Chris Lacy, Jeff Carr and Jalen McCleskey all made a big impact, and are all young guys who show great promise.4. The November Gauntlet is Real (KB)My pregame talk was something like this:“Baylor hasn’t won here since Snyder was born!”*Tweets video of Bryce Petty turf monster*I went to the game and it wasn’t even close, Baylor was just the better team on Saturday. The skill players for Baylor were incredible and KD Cannon is a receiver with an incredibly bright future. The gauntlet is just awful, but the important thing to remember is that they’ve got another big one this weekend.“You can’t allow a loss to be a hangover,” Gundy said to ESPN. “Obviously we’re playing a team (Oklahoma) that beat that team (Baylor). Everybody’s got to get a smile on their face, hard as it is, and go to work.”5. OSU will panic on offense if you overwhelm them (KP)That was the first time all season I’ve seen OSU consistently run a series of “crap, we have to score now, let’s go deep and see what happens” plays. They got away with it and hung in the game because The President is The President and Mason Rudolph is really good at football, but it never really resembled what I would call a good plan. Or even a plan at all.If you’re looking for the comments section, it has moved to our forum, The Chamber. You can go there to comment and holler about these articles, specifically in these threads. You can register for a free account right here and will need one to comment.If you’re wondering why we decided to do this, we wrote about that here. Thank you and cheers!last_img read more

Read More »

CFL 2017: East Bengal 2-2 Mohammedan Sporting

first_imgCFL 2017: East Bengal manage a 2-2 draw against Mohammedan Sporting Ritabrata Banerjee Last updated 2 years ago 18:32 16/9/2017 East Bengal vs Mohammedan Mohammedan Sporting Mohammedan Sporting end East Bengal’s winning streak in the Calcutta Football League… After winning six consecutive matches in the Calcutta Football League, Khalid Jamil’s East Bengal finally fumbled in the seventh round against Mohammedan Sporting on Saturday. A 2-2 draw against the Black Panthers has left the league wide open as both the Red and Golds and Mohun Bagan are now tied on 19 points.Mahmoud Al Amna’s brilliant strike gave East Bengal the lead as early as in the second minute of the match. Mohammed Rafique’s curling free-kick was headed down by Arnab Mondal inside the Mohammedan penalty box and the Syrian midfielder chest trapped the ball before finding the back of the net with an excellent volley.The Red and Golds meant business from the very beginning of the match and got the early goal as a reward for their attacking display. Mohammedan on the other hand struggled to create chances in the attacking third and looked clueless against their opponents. Article continues below Editors’ Picks ‘I’m getting better’ – Can Man Utd flop Fred save his Old Trafford career? Why Barcelona god Messi will never be worshipped in the same way in Argentina Lyon treble & England heartbreak: The full story behind Lucy Bronze’s dramatic 2019 Liverpool v Man City is now the league’s biggest rivalry and the bitterness is growing But Biswajit Bhattacharya’s men got the equaliser against the run of play in the 20th minute. Dipendu Dowary played a lovely ball for Kalu Ogba on the right side who quickly directed it towards an unmarked Jiten Murmu with his outstep. Taking advantage of a lazy East Bengal defence, Murmu made no mistake in finding the back of the net.Khalid Jamil made two quick changes in the second-half introducing Gabriel Fernandes and Surabuddin Mullick in place of Joby Justin and Laldanmawia Ralte.East Bengal dominated the proceedings in the second-period too but failed to score the crucial second goal. A total of three genuine chances were all squandered as the ball rebounded off the post on all three occasions.East Bengal vs MohammedanOnce again against the run of play Dipanda Dicka handed Mohammedan the lead from Jiten Murmu’s cross as the vulnerability in East Bengal’s backline was exposed.A desperate Jamil brought in Cavin Lobo in the 80th minute. Lobo’s introduction in the match proved to be a masterstroke as from the midfielder’s pass Willis Plaza equalised just three minutes before the 90-minute mark.Lobo created space brilliantly for Plaza on the right side of the penalty box and the Trinidadian forward launched a scintillating shot to find the back of the net.Both East Bengal and Mohun now have the same amount of points with two games left. A win for both sides in their next encounters would imply that the Kolkata derby on September 24 becomes the title decider.The draw against Mohammedan exposed several loopholes in Khalid Jamil’s side. The defence is yet to combine properly and are getting exposed quite easily in every match. Also, the team lacks a proper defensive midfielder which is affecting side on counter-attacks. read morelast_img read more

Read More »